Technical Basis of the endTB Observational Study (EN/RU/ES/FR)

January 20, 2019

The endTB (Expand New Drug Markets for TB) consortium consists of three NGOs: Partners In Health (PIH), Médecins Sans Frontières (MSF) and Interactive Research and Development (IRD). Funded by Unitaid, the objective of endTB is to promote better and safer MDR-TB treatment regimens. The endTB Observational Study currently has sites in 17 countries. In each country, sites enroll patients on treatment with bedaquiline and delamanid according to National TB Program guidelines, while collecting clinical and bacteriological data related to efficacy and safety.

DR-TB Drugs Under the Microscope: 5th edition

November 26, 2018

This MSF Access Campaign report – now in its fifth edition – analyses the barriers and factors affecting access to treatment regimens for drug-resistant tuberculosis (DR-TB), including new and repurposed drugs.

We provide detailed pricing profiles of key DR-TB drugs, using manufacturer responses to standardised questionnaires and the Global TB Drug Facility website.

This report was produced with endTB's support.

endTB Clinical Guide v4.0 (EN / RU / ES / FR)

February 9, 2018

This guide is designed to give guidance to the endTB Project site on the use of new TB drugs bedaquiline and delamanid.

It is intended to be a resource for physicians and other health care professionals involved in the endTB project.

The clinical guide is available in English, Russian, Spanish and French.

eLearning modules

February 8, 2018
​​​​​​The following eLearning units have been developed to provide guidance to physicians caring for MDR-TB patients enrolled in the endTB project.

Patent Opposition Database

January 10, 2018

The Patent Opposition Database is a site that allows civil society to share resources and learn about the tools needed to oppose the application or granting of unwarranted patents on medicines. The site contains a wealth of information on existing patent oppositions, patent applications, patent office decisions, court cases and other vital documents that will inform users own preparation for filing an opposition by sharing these resources and the experience of others.

Out of Step: TB policies in 29 countries, 3rd Ed. (2017)

September 19, 2017

Although it can be prevented and successfully treated, tuberculosis (TB) is the world’s deadliest infectious disease: in 2015, 1.8 million people died from it. While there have been substantial and important innovations in the fight against TB, including faster, more accurate diagnostic tests and the first new medicines in nearly 50 years, deadly gaps remain in implementing and providing access to these advances.

Terms of reference: endTB Medical Committee

May 13, 2017

The endTB Medical Committee formulates recommendations for off-label and compassionate use of the new anti-TB drugs for M(X)DR-TB.

It provides advice to any MSF, PIH and IRD projects for individual patient’s management on a case-by-case basis in answer to requests initiated by clinicians from the projects.

For more information, please download the terms of reference.